NFL Week 6 Players Team Injury Report List 2025, USA NFL Live Injury Reports Today, NFL Schedule

the latest on NFL Week 6 injury reports based on available updates. Note that final statuses may shift after today’s practices and official reports released by teams. Key updates for games on October 12 include:
- Tampa Bay Buccaneers vs. San Francisco 49ers (4:25 p.m. ET):
- Buccaneers: OT Tristan Wirfs (knee) is limited in practice, a concern for Mayfield’s protection. WR Mike Evans (hamstring) and WR Chris Godwin (hamstring) are returning to practice, boosting the offense. No major QB injuries reported for Mayfield.
- 49ers: QB Brock Purdy (toe) is out, with Mac Jones starting. Several defensive players are on injured reserve, including Nick Bosa (EDGE), potentially weakening their pass rush against Mayfield.
- Other Notable Injuries:
- Kyler Murray (Cardinals, foot): DNP in Wednesday practice but expected to play vs. Colts, though mobility may be limited.
- Lamar Jackson (Ravens, hamstring): Missed Wednesday practice vs. Rams; status uncertain but critical for their offense.
- Omarion Hampton (Chargers, ankle): Placed on IR, out at least four games vs. Dolphins.
- Saquon Barkley (Eagles, knee): DNP in Monday’s estimated practice vs. Giants; status questionable.